Release date: 2017-09-14
Recently, scientists have developed a new type of "electronic gene" therapy that is expected to provide a revolutionary treatment for heart disease.
Heart disease is the highest rate of death in Europe. In 2013 alone, 1.9 million people died of cardiovascular disease, accounting for 37.5% of the total number of deaths that year.
People with a higher risk of heart rhythm disorders often transplant a cardiac defibrillator by surgery. However, what if the heart itself can detect and repair its own symptoms? This is the problem that Dr. D?niel Pijnappels, a cardiologist from the Medical Center in Leiden University in the Netherlands, is working on.
(Source: 'Cardiac amyloidosis very high mag movat' by Nephron licenced by CC 3.0 unported)
His idea was to let the heart identify the signs of its own rhythm disorder and bring the heartbeat rhythm back on track by the electrical signal that got up, and the means to achieve this was through virus transfection. Rhythm recognition and correction "related genes are transferred into heart cells. "This protein is not only a detector for identifying tremors, but also a correction for rhythm abnormalities," explains Dr. Pijnappels.
This new "biological" defibrillator has significant advantages over today's electronic devices: first, it avoids surgical procedures that are prone to side effects, and circumvents the limitations inherent in electronic devices, such as battery life and equipment. Aging and software failures, etc.
Dr. Pijnappels hopes that the defibrillator he developed will not cause other reactions in the body, and will be able to correct the abnormal rhythm of the heart.
In fact, the symptoms of heart rhythm disorders occur not only in the frail elderly population, but also in the adolescent population due to changes in heart rhythm caused by excessive exercise. In addition, because some people live in related genetic defects, there are also High risk of heart rhythm disorders. If this technology can enter clinical practice, it will have a very good therapeutic effect on the above population.
Source: Bio Valley (WeChat: BIOONNEWS)
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