September 9: Taiwanese scientists and technicians have succeeded in naturally reproducing the next generation of cloned sheep. According to Taiwan Media, the Taiwan Animal Husbandry Laboratory jointly announced the news with the Department of Animal Husbandry of Taiwan University, the Department of Life Sciences of Chung Hsing University, and the Department of Veterinary and Livestock of Pingtung University of Science and Technology. The Institute of Animal Husbandry stated that on July 5, 2002, two sheep were successfully cloned from somatic cells of a high-emulsion ewes and were named “Baoji†and “Baoxiangâ€, respectively, and their growth was normal. On September 21, 2004, Baoxiang was pregnant through natural mating and gave birth on February 17 this year. It produced a male and a female and two lambs. The two lambs have grown no different from ordinary goats. And Baoxiang came from the somatic cell of the same pioneer ewes, but also added an exogenous gene for the treatment of human hemophilia A type "eight factor-VIII". It was also successful on March 10, 2004. The first cloned sheep with foreign genes identified in Taiwan was cloned and named "Bao Xi", which is also the sister of Bao Ji and Bao Xiang. Excitingly, Baodi is a lively and healthy goat. It was pregnant on November 26 last year. It was delivered on April 25 this year. It gave birth to a small ram and now it grows to 23.5 kg. . The unnamed young ram has already detected the exogenous gene that is confirmed to contain the human eighth clotting factor, and successfully demonstrated that the transgenic cloned animal can grow, mating, become pregnant, and give birth. Chen Liren, director of the Molecular Biological Unit of the Institute of Animal Husbandry, said that “transgenic replication animals†can grow smoothly and deliver their babies normally, and that exogenous genes are transmitted to the next generation through breeding. This has a major impact on the establishment of “molecular ranch†that all parties expect. Although there is still some distance from the birth of biomedical products, at least it has been successful and has taken a major first step.
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