Application status of pharmaceutical flexible packaging materials

Strip Packaging Film SP (StripPackaging)

It uses two layers of medicinal strip packaging film (SP) to sandwich the medicine in the middle, and the distance between the unit medicines is separated by a certain interval. The two layers of SP film near the medicine are heat-sealed and sealed on the strip vacuum packaging equipment. The unit is in the form of a unit package. The strip package is a continuous work on the strip vacuum packaging equipment. It is especially suitable for large-volume automatic packaging. When the medicine is taken, the SP film can be torn along the tooth marks. However, the use of a single dose of the drug does not affect the packaging and storage of other drugs. For some larger dosage forms of pharmaceutical packaging, it is required to have strong hygroscopicity, anti-ultraviolet light, heat and cold resistance, and drugs requiring a long period of validity can be used in such packaging.

The strip-shaped packaging printing film is an aluminum-plastic composite film having a certain tensile strength and elongation, and is suitable for solid medicines of various shapes and sizes, and is less prone to cracking and wrinkles. At present, the commonly used aluminum-plastic composite film is: PT/AL/PE (cello/aluminum foil/polyethylene) composite, PET/AL/PE (polyester/aluminum foil/polyethylene) composite, aluminum foil and plastic film to bond The agent is laminated or extruded. The internal structure is composed of a base layer, a printing layer, a high barrier layer, and a sealing layer. The base layer is outside, the heat seal layer, the high barrier layer and the print layer are located in the middle, and the mechanical properties of the base material are required to be excellent, shiny, good in printability, good in barrier properties, safe and non-toxic. The base printing materials used are PET® PT and cellophane with PVDC coating. The high barrier layer has good gas barrier properties and is moisture-proof, non-permeable to bacteria and microorganisms, has good mechanical function, has a certain elongation, is resistant to cold and heat, is safe and non-toxic, and the typical material used is soft aluminum foil. This soft aluminum foil is opaque, rust-free and has a strong light-shielding property. If a transparent strip packaging film is required, PVDC is used as a high barrier material to block the gas and water vapor, which can maintain the original effect of the drug. The sealing layer is the inner layer of the strip packaging film and has excellent heat sealing. Sex, chemically non-disruptive and hygienic, LDPE (low density polyethylene) materials are available. At present, foreign medicinal strip packaging films have been developed from double layers to multilayer composites.

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