For the first time in the world: Japan will launch a clinical study of iPS cell allograft

Release date: 2016-06-08

Four organizations, including the Japan Institute of Physical Chemistry, released a message in Kobe on the 6th of this month that it will restart retinal cells cultured from artificially induced pluripotent stem cells (iPS cells) made from other cells to "exudative age-related macular degeneration." "Clinical research on patients.

According to reports, the researchers will use the "iPS cell bank" of the Kyoto University to store iPS cells made from cells of a special population that are alleged to have less rejection during transplantation. "Immune transplantation" with this iPS cell is the first in the world and will be restarted in a new way.

In September 2014, Japan completed the world's first operation using a cell cultured with iPS cells for transplantation. The second operation was interrupted by a genetic mutation in the patient's iPS cells.

In the clinical study, in addition to the relatively low cost, time-saving and high quality Kyoto University "iPS cell bank", iPS cells made of the patient's own cells can be used as in the first surgery.

In two ways, a retinal pigment epithelial cell cultured with iPS cells is used as a film for transplantation, and a liquid containing pigment epithelial cells is injected into the damaged retina. In the future, we will strive to conduct clinical trials on 20 patients to confirm whether cancer will occur.

Source: China News Network

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