(A) Vitamin B6 should be used together with hydralazine (antihypertensives). Long-term or higher doses of hydralazine can cause vitamin B6 deficiency, and the two drugs can prevent their lack.
(b) Vitamin B6 should be used together with ATP (adenosine triphosphate). Because vitamin B6 is involved in the metabolism of body fat, protein, sugar, nucleic acid, and nucleotides, it helps to improve the efficacy of ATP.
(c) Vitamin B6 should be combined with penicillamine. Penicillamine commonly used in clinical treatment of hepatolenticular degeneration or schizophrenia, but long-term medication can cause vitamin B6 deficiency. Therefore, long-term use of penicillamine should be supplemented with vitamin B6.
(D) VB6 should be combined with oral contraceptives. The long-term use of estrogen and progesterone preparations can reduce the content of vitamin B6 in plasma, which is related to the effect of estrogen-promoting drug enzyme activity. Reported that: long-term oral contraceptives can cause depression, cured by vitamin B6. Obviously, the combination of the two can prevent the decrease of vitamin B6 in plasma and depression.
(E) Vitamin B6 should be combined with vitamin C: There is information that: taking large doses of Vc may occur urinary tract stones oxalic acid. Because vitamin B6 can interfere with the human oxalate acid production and prevent stone formation, the two can be used together.
Vitamin B6 taking "five not":
(1) Vitamin B6 should not be used in combination with ferrous sulfate and iron-rich iron. Because iron can increase the toxicity of vitamin B6, the efficacy decreases.
(b) Vitamin B6 should not be used with cycloserine (anti-tuberculosis drugs). This is because the latter can antagonize the former and cause vitamin B6 deficiency anemia. The combination of anemia and aggravation of long-term combined use of the two drugs should not be combined.
(c) Vitamin B6 should not be used with levodopa. Levodopa is an effective drug for the treatment of paralysis and paralysis. The combination of them can rapidly weaken and eliminate the anti-shock effect of levodopa, and the symptoms of paralysis and paralysis increase. This may be related to vitamin B6 accelerating the dehydroxylation and transport of levodopa.
(4) Vitamin B6 injection should not be used together with dexamethasone injection. This is because the former is water-soluble alkaline, the latter is acidic, acid-base combination of precipitation, so that increased drug toxicity, and greatly reduced efficacy, it should not be combined.
(e) Vitamin B6 should not be used in combination with isoniazid. Since the discovery of isoniazid caused the excretion of vitamin B6 in the urine to increase, resulting in vitamin B6 deficiency, since the initiation of neuritis, vitamin B6 is often combined with isoniazid. However, in recent years, medical experts have confirmed that vitamin B6 and isoniazid have a competitive antagonistic effect in vivo, which can lead to the lack of vitamin B6, so it should not be used at the same time. Long-term use and doses of isoniazid patients appear vitamins
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