H5N6 Reproduction Expert Says No Outbreak Evidence

On December 27th, in response to the recent report of the second case of H5N6 infection in Guangzhou, the deputy director of the State Key Laboratory of Respiratory Diseases of the Guangzhou Institute of Respiratory Diseases, Chen Ling, told reporters that the two cases of H5N6 infection so far occurred In sporadic cases, there is currently no evidence that H5N6 will have an outbreak similar to H7N9. "But we still need to be highly vigilant. Individuals should stay away from live birds as much as possible. Grass-roots hospitals must also observe closely." Chen Ling also stressed.

On December 23, the Guangdong Provincial Health and Family Planning Commission notified that a positive H5N6 bird flu virus nucleic acid was detected in one case of severe pneumonia. The patient, a 58-year-old man living in Panyu District of Guangzhou, had colon cancer surgery last year. According to the reporter’s understanding, the family of the patient had informed the attending doctor that the patient had purchased a live chicken at the general market near Changxi, Hanxi, after December 22, and had been raining home all along. The patient first visited a primary hospital and was transferred to the First Affiliated Hospital of Guangzhou Medical University after the condition became worse. As of press time, the patient was still receiving treatment in the intensive care unit.

The National Health and Family Planning Commission organized an expert to confirm that the incidents that occurred were incidental cases. There was no abnormality in all close contacts of the case and there was no case of human transmission. Chen Ling said: "There is no evidence that the outbreak of H5N6. CDC, the agricultural sector need to further monitor and analyze the distribution of the virus in birds in order to assess the risk of H5N6."

On December 27th, the Beijing Municipal Center for Disease Control and Prevention issued the H5N6 bird flu prevention measures. It is recommended that the public avoid contact with live poultry. When poultry meat and eggs are eaten, they should be fully cooked and symptoms should be treated promptly.

Chen Ling said: "Avoid contact with live birds can greatly reduce the possibility of infection. At the same time, primary hospitals should be vigilant, send samples as soon as possible to carry out the detection of influenza patients, seize the golden time for treatment, the hope of bird flu cure It's bigger."

It is reported that the vaccine development for the H5N6 virus has not yet started. "Vaccination is the most effective means to prevent influenza virus infection, but the premise is that there has been a large-scale human-to-human infection," the experts said.

From April 8th to 20th this year, researchers of the State Key Laboratory for Respiratory Diseases obtained genetic information for the H7N9 virus, and through gene synthesis and the use of reverse genetic virus rescue techniques, they obtained animals for a short period of 12 days. Experimental H7N9 recombinant virus vaccine strain (AH-H7N9-PR8).

On May 6, 2014, according to the Sichuan Provincial Health and Family Planning Commission, the province was diagnosed with 1 case of human infection with H5N6 subtype of bird flu. This is the first time that the virus has been found to infect humans in the world. The H5N6 subtype bird flu virus was isolated from ducks and wild ducks in Germany, Sweden, the United States, and Taiwan in China, and was mostly a low-pathogenic avian influenza virus. Since this year, H5N6 subtype highly pathogenic avian influenza virus has been found among poultry in Nanchong, Sichuan Province, Harbin, Heilongjiang Province, Laos and Vietnam.